By definition, clodronate liposome is a drug delivered using liposome (a synthetic lipid that encapsulates other substances for ease of administration into the body). Liposome is manly a medium which carries the highly hydrophilic Clodronate thus facilitating its transport into the target organ. Essentially, the aim of this type of drug administration is to achieve higher macrophage depletion after an intravenous injection of the drug.
Like a Trojan horse, liposome carriers clodronate to the target cell where it is ingested by the macrophages. This then releases the drug into the cell and the inhibition of the macrophages activities is achieved by bisphosphonates (the active components in it). Though the idea looks simple, researchers are upbeat that this will be the best cure for most stubborn immune diseases.
Examples of the disease this drug is expected to treat include metastatic carcinomas of the breast, multiple myeloma and osteoporosis. It is also expected to be the best solution for autoimmune hyemolitic anemia, cancers and tumors in general. Significant strides have also been made with the drug during tests as far as inhibition of macrophages activities in therapies such gene and transplantation. Even in the handling of neurological disorders, this drug will be the best.
As with every most bisphosphonates, there are no major side effects associated with Clodronate. In fact, it is expected to have similar effects that other drugs in this category have shown. For instance, those undergoing treatment against high calcium levels in the blood do complain of mild stomach pains, nausea and vomiting. Other mild side effects include diarrhea and loss of appetite.
While the above-mentioned adverse effects are considered mild and often disappear without further medication, other symptoms should not be taken lightly. There are however some rare cases where bisphosphonates have resulted in serious complications that warrant the attention of a doctor. Individuals should therefore be careful while taking the drug since it may also have serious side effects such as such wheezing or difficult breathing.
Additional complications such as unknown malaise, swelling of body parts and mouth pain should also be treated with caution. Physicians in such cases may recommend treatment or drug discontinuation. It is important to note that these are not recorded drug reactions from the drug since it has not been fully put into human use. You should therefore not be discouraged in anyway.
Some general contraindications are common with most prescription drugs. For instance, you should not take the drug if you are allergic to Clodronates or bisphosphonates. Similarly, expecting or breastfeeding mothers should not use the drug. Patients with kidney problems or using other bisphosphonate drugs should not use the drug too. It is also advisable that you stay from these types of drugs if you have inflammation of the gastro intestines.
Clodronate liposome as mentioned before is a prescription drug and thus cannot be shared with a family member, even if they have the same conditions. On the other hand, one cannot use the drugs unless the doctor prescribes it. Once it is officially released, it is expected to bring the much-needed cure for cancer. However, success will depend on how strict the patients will follow the prescription of the doctor.
Like a Trojan horse, liposome carriers clodronate to the target cell where it is ingested by the macrophages. This then releases the drug into the cell and the inhibition of the macrophages activities is achieved by bisphosphonates (the active components in it). Though the idea looks simple, researchers are upbeat that this will be the best cure for most stubborn immune diseases.
Examples of the disease this drug is expected to treat include metastatic carcinomas of the breast, multiple myeloma and osteoporosis. It is also expected to be the best solution for autoimmune hyemolitic anemia, cancers and tumors in general. Significant strides have also been made with the drug during tests as far as inhibition of macrophages activities in therapies such gene and transplantation. Even in the handling of neurological disorders, this drug will be the best.
As with every most bisphosphonates, there are no major side effects associated with Clodronate. In fact, it is expected to have similar effects that other drugs in this category have shown. For instance, those undergoing treatment against high calcium levels in the blood do complain of mild stomach pains, nausea and vomiting. Other mild side effects include diarrhea and loss of appetite.
While the above-mentioned adverse effects are considered mild and often disappear without further medication, other symptoms should not be taken lightly. There are however some rare cases where bisphosphonates have resulted in serious complications that warrant the attention of a doctor. Individuals should therefore be careful while taking the drug since it may also have serious side effects such as such wheezing or difficult breathing.
Additional complications such as unknown malaise, swelling of body parts and mouth pain should also be treated with caution. Physicians in such cases may recommend treatment or drug discontinuation. It is important to note that these are not recorded drug reactions from the drug since it has not been fully put into human use. You should therefore not be discouraged in anyway.
Some general contraindications are common with most prescription drugs. For instance, you should not take the drug if you are allergic to Clodronates or bisphosphonates. Similarly, expecting or breastfeeding mothers should not use the drug. Patients with kidney problems or using other bisphosphonate drugs should not use the drug too. It is also advisable that you stay from these types of drugs if you have inflammation of the gastro intestines.
Clodronate liposome as mentioned before is a prescription drug and thus cannot be shared with a family member, even if they have the same conditions. On the other hand, one cannot use the drugs unless the doctor prescribes it. Once it is officially released, it is expected to bring the much-needed cure for cancer. However, success will depend on how strict the patients will follow the prescription of the doctor.
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